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arxiv_cv 95% Match Research Paper Medical Imaging Researchers,Radiologists,Medical Physicists,AI Researchers in Healthcare 2 weeks ago

X$^{2}$-Gaussian: 4D Radiative Gaussian Splatting for Continuous-time Tomographic Reconstruction

computer-vision › medical-imaging
📄 Abstract

Abstract: Four-dimensional computed tomography (4D CT) reconstruction is crucial for capturing dynamic anatomical changes but faces inherent limitations from conventional phase-binning workflows. Current methods discretize temporal resolution into fixed phases with respiratory gating devices, introducing motion misalignment and restricting clinical practicality. In this paper, We propose X$^2$-Gaussian, a novel framework that enables continuous-time 4D-CT reconstruction by integrating dynamic radiative Gaussian splatting with self-supervised respiratory motion learning. Our approach models anatomical dynamics through a spatiotemporal encoder-decoder architecture that predicts time-varying Gaussian deformations, eliminating phase discretization. To remove dependency on external gating devices, we introduce a physiology-driven periodic consistency loss that learns patient-specific breathing cycles directly from projections via differentiable optimization. Extensive experiments demonstrate state-of-the-art performance, achieving a 9.93 dB PSNR gain over traditional methods and 2.25 dB improvement against prior Gaussian splatting techniques. By unifying continuous motion modeling with hardware-free period learning, X$^2$-Gaussian advances high-fidelity 4D CT reconstruction for dynamic clinical imaging. Code is publicly available at: https://x2-gaussian.github.io/.
Authors (6)
Weihao Yu
Yuanhao Cai
Ruyi Zha
Zhiwen Fan
Chenxin Li
Yixuan Yuan
Submitted
March 27, 2025
arXiv Category
cs.CV
arXiv PDF

Key Contributions

Proposes X$^2$-Gaussian, a novel framework for continuous-time 4D CT reconstruction by integrating dynamic radiative Gaussian splatting with self-supervised respiratory motion learning. It eliminates phase discretization and removes dependency on external gating devices by learning breathing cycles directly from projections.

Business Value

Improved 4D CT reconstruction can lead to more accurate diagnosis and treatment planning for dynamic diseases (e.g., lung cancer), potentially reducing radiation exposure and improving patient outcomes.