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📄 Abstract
Abstract: Frontier AI agents show increasing promise as scientific research assistants,
and may eventually be useful for extended, open-ended research workflows.
However, in order to use agents for novel research, we must first assess the
underlying faithfulness and correctness of their work. To evaluate agents as
research assistants, we introduce ReplicationBench, an evaluation framework
that tests whether agents can replicate entire research papers drawn from the
astrophysics literature. Astrophysics, where research relies heavily on
archival data and computational study while requiring little real-world
experimentation, is a particularly useful testbed for AI agents in scientific
research. We split each paper into tasks which require agents to replicate the
paper's core contributions, including the experimental setup, derivations, data
analysis, and codebase. Each task is co-developed with the original paper
authors and targets a key scientific result, enabling objective evaluation of
both faithfulness (adherence to original methods) and correctness (technical
accuracy of results). ReplicationBench is extremely challenging for current
frontier language models: even the best-performing language models score under
20%. We analyze ReplicationBench trajectories in collaboration with domain
experts and find a rich, diverse set of failure modes for agents in scientific
research. ReplicationBench establishes the first benchmark of paper-scale,
expert-validated astrophysics research tasks, reveals insights about agent
performance generalizable to other domains of data-driven science, and provides
a scalable framework for measuring AI agents' reliability in scientific
research.
Authors (13)
Christine Ye
Sihan Yuan
Suchetha Cooray
Steven Dillmann
Ian L. V. Roque
Dalya Baron
+7 more
Submitted
October 28, 2025
Key Contributions
Introduces ReplicationBench, an evaluation framework to test AI agents' ability to replicate entire astrophysics research papers. It splits papers into tasks covering experimental setup, derivations, data analysis, and codebase, co-developed with authors for objective evaluation of AI as scientific research assistants.
Business Value
Enables reliable integration of AI agents into scientific workflows, accelerating discovery and ensuring research integrity.